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Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2

BACKGROUND: Macrophages are innate immune cells with diverse functional and molecular phenotypes. This diversity is largely unexplored at the level of single-cell proteomes because of the limitations of quantitative single-cell protein analysis. RESULTS: To overcome this limitation, we develop SCoPE...

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Detalles Bibliográficos
Autores principales: Specht, Harrison, Emmott, Edward, Petelski, Aleksandra A., Huffman, R. Gray, Perlman, David H., Serra, Marco, Kharchenko, Peter, Koller, Antonius, Slavov, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839219/
https://www.ncbi.nlm.nih.gov/pubmed/33504367
http://dx.doi.org/10.1186/s13059-021-02267-5