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Hemokinin-1 as a Mediator of Arthritis-Related Pain via Direct Activation of Primary Sensory Neurons

The tachykinin hemokinin-1 (HK-1) is involved in immune cell development and inflammation, but little is known about its function in pain. It acts through the NK1 tachykinin receptor, but several effects are mediated by a yet unidentified target. Therefore, we investigated the role and mechanism of...

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Detalles Bibliográficos
Autores principales: Borbély, Éva, Hunyady, Ágnes, Pohóczky, Krisztina, Payrits, Maja, Botz, Bálint, Mócsai, Attila, Berger, Alexandra, Szőke, Éva, Helyes, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839295/
https://www.ncbi.nlm.nih.gov/pubmed/33519457
http://dx.doi.org/10.3389/fphar.2020.594479