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Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low levels

Risk‐reducing bilateral salpingo‐oophorectomy (RRBSO) is highly effective for the prevention of high‐grade serous ovarian cancer (HGSOC) in BRCA1/2 pathogenic variant carriers (PVCs), but does not completely eliminate future risk of primary peritoneal cancer (PPC). The requirement to completely remo...

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Detalles Bibliográficos
Autores principales: Crosbie, Emma J., Flaum, Nicola, Harkness, Elaine F., Clayton, Richard D., Holland, Cathrine, Martin‐Hirsch, Pierre, Wood, Nick, Keating, Patrick, Woodward, Emma R., Lalloo, Fiona, Donnai, Paul, Edmondson, Richard J., Evans, D. Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839461/
https://www.ncbi.nlm.nih.gov/pubmed/33152107
http://dx.doi.org/10.1002/ijc.33378