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Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self‐renewal
The self‐renewal efficiency of mouse embryonic stem cells (ESCs) is determined by the concentration of the transcription factor NANOG. While NANOG binds thousands of sites in chromatin, the regulatory systems that control DNA binding are poorly characterised. Here, we show that NANOG is phosphorylat...
Autores principales: | Mullin, Nicholas P., Varghese, Joby, Colby, Douglas, Richardson, Julia M., Findlay, Greg M., Chambers, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839479/ https://www.ncbi.nlm.nih.gov/pubmed/33107035 http://dx.doi.org/10.1002/1873-3468.13969 |
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