A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes

Genome‐wide association studies (GWAS) have identified single‐nucleotide polymorphisms (SNPs) associated with glioma risk on 20q13.33, but the biological mechanisms underlying this association are unknown. We tested the hypothesis that a functional SNP on 20q13.33 impacted the activity of an enhance...

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Detalles Bibliográficos
Autores principales: Ali, Mourad Wagdy, Patro, C. Pawan K., Zhu, Jacqueline Jufen, Dampier, Christopher H., Plummer, Sarah J., Kuscu, Cem, Adli, Mazhar, Lau, Ching, Lai, Rose K., Casey, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839675/
https://www.ncbi.nlm.nih.gov/pubmed/33169458
http://dx.doi.org/10.1002/humu.24134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839675/
https://www.ncbi.nlm.nih.gov/pubmed/33169458
http://dx.doi.org/10.1002/humu.24134

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