Cargando…
Autophagy in white matter disorders of the CNS: mechanisms and therapeutic opportunities
Autophagy is a constitutive process that degrades, recycles and clears damaged proteins or organelles, yet, despite activation of this pathway, abnormal proteins accumulate in neurons in neurodegenerative diseases and in oligodendrocytes in white matter disorders. Here, we discuss the role of autoph...
Autores principales: | Nutma, Erik, Marzin, Manuel C, Cillessen, Saskia AGM, Amor, Sandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839724/ https://www.ncbi.nlm.nih.gov/pubmed/33135781 http://dx.doi.org/10.1002/path.5576 |
Ejemplares similares
-
Imaging immunological processes from blood to brain in amyotrophic lateral sclerosis
por: Amor, Sandra, et al.
Publicado: (2021) -
Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders
por: Pinho, Andreia G., et al.
Publicado: (2020) -
Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain
por: Nutma, Erik, et al.
Publicado: (2021) -
Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter
por: Miedema, Anneke, et al.
Publicado: (2022) -
An in vitro model for studying CNS white matter: functional properties and experimental approaches
por: Bijland, Silvia, et al.
Publicado: (2019)