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Boronic Acid‐Mediated Activity Control of Split 10–23 DNAzymes
The 10–23 DNAzyme is an artificially developed Mg(2+)‐dependent catalytic oligonucleotide that can cleave an RNA substrate in a sequence‐specific fashion. In this study, new split 10–23 DNAzymes made of two nonfunctional fragments, one of which carries a boronic acid group at its 5′ end, while the o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839725/ https://www.ncbi.nlm.nih.gov/pubmed/33058268 http://dx.doi.org/10.1002/chem.202004227 |