Cargando…

Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

Our recent genomic studies identified a complex kidney‐specific enhancer module located within the introns of adjacent Mettl1 (M1) and Mettl21b (M21) genes that mediate basal and PTH induction of Cyp27b1, as well as suppression by FGF23 and 1,25‐dihydroxyvitamin D(3) [1,25(OH)(2)D(3)]. The tissue sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Pike, J Wesley, Lee, Seong Min, Benkusky, Nancy A, Meyer, Mark B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839818/
https://www.ncbi.nlm.nih.gov/pubmed/33553989
http://dx.doi.org/10.1002/jbm4.10433