Cargando…

A novel cyclic peptide (Naturido) modulates glia–neuron interactions in vitro and reverses ageing-related deficits in senescence-accelerated mice

The use of agents that target both glia and neurons may represent a new strategy for the treatment of ageing disorders. Here, we confirmed the presence of the novel cyclic peptide Naturido that originates from a medicinal fungus (Isaria japonica) grown on domestic silkworm (Bombyx mori). We found th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishiguro, Shinichi, Shinada, Tetsuro, Wu, Zhou, Karimazawa, Mayumi, Uchidate, Michimasa, Nishimura, Eiji, Yasuno, Yoko, Ebata, Makiko, Sillapakong, Piyamas, Ishiguro, Hiromi, Ebata, Nobuyoshi, Ni, Junjun, Jiang, Muzhou, Goryo, Masanobu, Otsu, Keishi, Harada, Hidemitsu, Suzuki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840003/
https://www.ncbi.nlm.nih.gov/pubmed/33503058
http://dx.doi.org/10.1371/journal.pone.0245235