A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics

Artificial nucleic acid circuits with precisely controllable dynamic and function have shown great promise in biosensing, but their utility in molecular diagnostics is still restrained by the inability to process genomic DNA directly and moderate sensitivity. To address this limitation, we present a...

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Detalles Bibliográficos
Autores principales: Shi, Kai, Xie, Shiyi, Tian, Renyun, Wang, Shuo, Lu, Qin, Gao, Denghui, Lei, Chunyang, Zhu, Haizhen, Nie, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840123/
https://www.ncbi.nlm.nih.gov/pubmed/33571114
http://dx.doi.org/10.1126/sciadv.abc7802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840123/
https://www.ncbi.nlm.nih.gov/pubmed/33571114
http://dx.doi.org/10.1126/sciadv.abc7802

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