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A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics
Artificial nucleic acid circuits with precisely controllable dynamic and function have shown great promise in biosensing, but their utility in molecular diagnostics is still restrained by the inability to process genomic DNA directly and moderate sensitivity. To address this limitation, we present a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840123/ https://www.ncbi.nlm.nih.gov/pubmed/33571114 http://dx.doi.org/10.1126/sciadv.abc7802 |