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EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer–cell interfaces

Paramyxovirus membrane fusion requires an attachment protein that binds to a host cell receptor and a fusion protein that merges the viral and host membranes. For Nipah virus (NiV), the G attachment protein binds ephrinB2/B3 receptors and activates F-mediated fusion. To visualize dynamic events of t...

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Detalles Bibliográficos
Autores principales: Wong, Joyce J., Chen, Zhongwen, Chung, Jean K., Groves, Jay T., Jardetzky, Theodore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840137/
https://www.ncbi.nlm.nih.gov/pubmed/33571127
http://dx.doi.org/10.1126/sciadv.abe1235