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The structure of the actin filament uncapping complex mediated by twinfilin

Uncapping of actin filaments is essential for driving polymerization and depolymerization dynamics from capping protein–associated filaments; however, the mechanisms of uncapping leading to rapid disassembly are unknown. Here, we elucidated the x-ray crystal structure of the actin/twinfilin/capping...

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Detalles Bibliográficos
Autores principales: Mwangangi, Dennis M., Manser, Edward, Robinson, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840138/
https://www.ncbi.nlm.nih.gov/pubmed/33571120
http://dx.doi.org/10.1126/sciadv.abd5271