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PHGDH as a mechanism for resistance in metabolically-driven cancers

At the forefront of cancer research is the rapidly evolving understanding of metabolic reprogramming within cancer cells. The expeditious adaptation to metabolic inhibition allows cells to evolve and acquire resistance to targeted treatments, which makes therapeutic exploitation complex but achievab...

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Detalles Bibliográficos
Autores principales: Rathore, Richa, Schutt, Charles R., Van Tine, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840151/
https://www.ncbi.nlm.nih.gov/pubmed/33511334
http://dx.doi.org/10.20517/cdr.2020.46