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Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact and traffic through subcellular sites to serve these essential functions is unknown. We show that RhopH is synthesized as a s...

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Detalles Bibliográficos
Autores principales: Schureck, Marc A, Darling, Joseph E, Merk, Alan, Shao, Jinfeng, Daggupati, Geervani, Srinivasan, Prakash, Olinares, Paul Dominic B, Rout, Michael P, Chait, Brian T, Wollenberg, Kurt, Subramaniam, Sriram, Desai, Sanjay A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840181/
https://www.ncbi.nlm.nih.gov/pubmed/33393463
http://dx.doi.org/10.7554/eLife.65282