Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics

Cell division control protein 42 homolog (Cdc42) protein, a Ras superfamily GTPase, regulates cellular activities, including cancer progression. Using all-atom molecular dynamics (MD) simulations and essential dynamic analysis, we investigated the structure and dynamics of the catalytic domains of G...

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Detalles Bibliográficos
Autores principales: Haspel, Nurit, Jang, Hyunbum, Nussinov, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840443/
https://www.ncbi.nlm.nih.gov/pubmed/33347888
http://dx.doi.org/10.1016/j.bpj.2020.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840443/
https://www.ncbi.nlm.nih.gov/pubmed/33347888
http://dx.doi.org/10.1016/j.bpj.2020.12.007

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