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Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics
Cell division control protein 42 homolog (Cdc42) protein, a Ras superfamily GTPase, regulates cellular activities, including cancer progression. Using all-atom molecular dynamics (MD) simulations and essential dynamic analysis, we investigated the structure and dynamics of the catalytic domains of G...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840443/ https://www.ncbi.nlm.nih.gov/pubmed/33347888 http://dx.doi.org/10.1016/j.bpj.2020.12.007 |