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Leaning Into the Bite: The piRNA Pathway as an Exemplar for the Genetic Engineering Need in Mosquitoes

The piRNA pathway is a specialized small RNA interference that in mosquitoes is mechanistically distant from analogous biology in the Drosophila model. Current genetic engineering methods, such as targeted genome manipulation, have a high potential to tease out the functional complexity of this intr...

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Detalles Bibliográficos
Autores principales: Macias, Vanessa M., Palatini, Umberto, Bonizzoni, Mariangela, Rasgon, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840538/
https://www.ncbi.nlm.nih.gov/pubmed/33520739
http://dx.doi.org/10.3389/fcimb.2020.614342