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Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms

Myeloid-derived Suppressor Cells (MDSCs) are a sub-population of leukocytes that are important for carcinogenesis and cancer immunotherapy. During carcinogenesis or severe infections, inflammatory mediators induce MDSCs via aberrant differentiation of myeloid precursors. Although several transcripti...

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Detalles Bibliográficos
Autores principales: Fultang, Norman, Li, Xinyuan, Li, Ting, Chen, Youhai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840597/
https://www.ncbi.nlm.nih.gov/pubmed/33519825
http://dx.doi.org/10.3389/fimmu.2020.619253