Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients

Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib. Peripheral blood from 30 NSCLC patients before, after 1 cycle of osimertinib and at progression of disease (PD) was analy...

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Detalles Bibliográficos
Autores principales: Ntzifa, Aliki, Strati, Areti, Kallergi, Galatea, Kotsakis, Athanasios, Georgoulias, Vassilis, Lianidou, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840727/
https://www.ncbi.nlm.nih.gov/pubmed/33504904
http://dx.doi.org/10.1038/s41598-021-82068-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840727/
https://www.ncbi.nlm.nih.gov/pubmed/33504904
http://dx.doi.org/10.1038/s41598-021-82068-9

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