Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...

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Detalles Bibliográficos
Autores principales: Liu, Yibin, Hu, Zhiyuan, Cheng, Jingfei, Siejka-Zielińska, Paulina, Chen, Jinfeng, Inoue, Masato, Ahmed, Ahmed Ashour, Song, Chun-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840749/
https://www.ncbi.nlm.nih.gov/pubmed/33504799
http://dx.doi.org/10.1038/s41467-021-20920-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840749/
https://www.ncbi.nlm.nih.gov/pubmed/33504799
http://dx.doi.org/10.1038/s41467-021-20920-2

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