Cargando…

Pericytes contribute to the islet basement membranes to promote beta-cell gene expression

β-Cells depend on the islet basement membrane (BM). While some islet BM components are produced by endothelial cells (ECs), the source of others remains unknown. Pancreatic pericytes directly support β-cells through mostly unidentified secreted factors. Thus, we hypothesized that pericytes regulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakhneny, Lina, Epshtein, Alona, Landsman, Limor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840750/
https://www.ncbi.nlm.nih.gov/pubmed/33504882
http://dx.doi.org/10.1038/s41598-021-81774-8