Cargando…
Pericytes contribute to the islet basement membranes to promote beta-cell gene expression
β-Cells depend on the islet basement membrane (BM). While some islet BM components are produced by endothelial cells (ECs), the source of others remains unknown. Pancreatic pericytes directly support β-cells through mostly unidentified secreted factors. Thus, we hypothesized that pericytes regulate...
Autores principales: | Sakhneny, Lina, Epshtein, Alona, Landsman, Limor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840750/ https://www.ncbi.nlm.nih.gov/pubmed/33504882 http://dx.doi.org/10.1038/s41598-021-81774-8 |
Ejemplares similares
-
Pericytes modulate islet immune cells and insulin secretion through Interleukin-33 production in mice
por: Burganova, Guzel, et al.
Publicado: (2023) -
Neonatal pancreatic pericytes support β-cell proliferation
por: Epshtein, Alona, et al.
Publicado: (2017) -
Isolating and Analyzing Cells of the Pancreas Mesenchyme by Flow Cytometry
por: Epshtein, Alona, et al.
Publicado: (2017) -
Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner
por: Hibsher, Daniel, et al.
Publicado: (2016) -
Pancreatic pericytes originate from the embryonic pancreatic mesenchyme
por: Harari, Neta, et al.
Publicado: (2019)