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IDH1 mutations induce organelle defects via dysregulated phospholipids
Infiltrating gliomas are devastating and incurable tumors. Amongst all gliomas, those harboring a mutation in isocitrate dehydrogenase 1 mutation (IDH1(mut)) acquire a different tumor biology and clinical manifestation from those that are IDH1(WT). Understanding the unique metabolic profile reprogra...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840755/ https://www.ncbi.nlm.nih.gov/pubmed/33504762 http://dx.doi.org/10.1038/s41467-020-20752-6 |