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Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
The generation of toxic amyloid β (Aβ) oligomers is a central feature of the onset and progression of Alzheimer’s disease (AD). Drug discoveries for Aβ oligomer degradation have been hampered by the difficulty of Aβ oligomer purification and a lack of screening tools. Here, we report a plasmonic nan...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840768/ https://www.ncbi.nlm.nih.gov/pubmed/33504788 http://dx.doi.org/10.1038/s41467-020-20611-4 |