MicroRNA-21 Inhibition Suppresses Alveolar M2 Macrophages in an Ovalbumin-Induced Allergic Asthma Mice Model

PURPOSE: MicroRNA-21 (miR-21) influences the Th2 immune pathway by suppressing the expressions of interleukin (IL)-12 and interferon (IFN)-γ. The effects of miR-21 suppression on alveolar macrophage polarization and airway inflammation are not known. METHODS: BALB/c and miR-21 knockout (KO) mice wer...

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Detalles Bibliográficos
Autores principales: Lee, Hwa Young, Hur, Jung, Kang, Ji Young, Rhee, Chin Kook, Lee, Sook Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840870/
https://www.ncbi.nlm.nih.gov/pubmed/33474864
http://dx.doi.org/10.4168/aair.2021.13.2.312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840870/
https://www.ncbi.nlm.nih.gov/pubmed/33474864
http://dx.doi.org/10.4168/aair.2021.13.2.312

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