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Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites
The macro domain is an ADP-ribose (ADPR) binding module, which is considered to act as a sensor to recognize nicotinamide adenine dinucleotide (NAD) metabolites, including poly ADPR (PAR) and other small molecules. The recognition of macro domains with various ligands is important for a variety of b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840908/ https://www.ncbi.nlm.nih.gov/pubmed/33504944 http://dx.doi.org/10.1038/s42003-020-01633-6 |