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Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites

The macro domain is an ADP-ribose (ADPR) binding module, which is considered to act as a sensor to recognize nicotinamide adenine dinucleotide (NAD) metabolites, including poly ADPR (PAR) and other small molecules. The recognition of macro domains with various ligands is important for a variety of b...

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Detalles Bibliográficos
Autores principales: Lin, Meng-Hsuan, Cho, Chao-Cheng, Chiu, Yi-Chih, Chien, Chia-Yu, Huang, Yi-Ping, Chang, Chi-Fon, Hsu, Chun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840908/
https://www.ncbi.nlm.nih.gov/pubmed/33504944
http://dx.doi.org/10.1038/s42003-020-01633-6