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Development of a target identification approach using native mass spectrometry

A key step in the development of new pharmaceutical drugs is the identification of the molecular target and distinguishing this from all other gene products that respond indirectly to the drug. Target identification remains a crucial process and a current bottleneck for advancing hits through the di...

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Detalles Bibliográficos
Autores principales: Liu, Miaomiao, Van Voorhis, Wesley C., Quinn, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840913/
https://www.ncbi.nlm.nih.gov/pubmed/33504855
http://dx.doi.org/10.1038/s41598-021-81859-4