Transcriptome-wide Mendelian randomization study prioritising novel tissue-dependent genes for glioma susceptibility

Genome-wide association studies (GWAS) have discovered 27 loci associated with glioma risk. Whether these loci are causally implicated in glioma risk, and how risk differs across tissues, has yet to be systematically explored. We integrated multi-tissue expression quantitative trait loci (eQTLs) and...

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Detalles Bibliográficos
Autores principales: Robinson, Jamie W., Martin, Richard M., Tsavachidis, Spiridon, Howell, Amy E., Relton, Caroline L., Armstrong, Georgina N., Bondy, Melissa, Zheng, Jie, Kurian, Kathreena M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840943/
https://www.ncbi.nlm.nih.gov/pubmed/33504897
http://dx.doi.org/10.1038/s41598-021-82169-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840943/
https://www.ncbi.nlm.nih.gov/pubmed/33504897
http://dx.doi.org/10.1038/s41598-021-82169-5

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