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Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis

Mycobacterium tuberculosis (Mtb) exposure drives antibody responses, but whether patients with active tuberculosis elicit protective antibodies, and against which antigens, is still unclear. Here we generate monoclonal antibodies from memory B cells of one patient to investigate the B cell responses...

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Detalles Bibliográficos
Autores principales: Watson, Avia, Li, Hao, Ma, Bingting, Weiss, Ronen, Bendayan, Daniele, Abramovitz, Lilach, Ben-Shalom, Noam, Mor, Michael, Pinko, Erica, Bar Oz, Michal, Wang, Zhenqi, Du, Fengjiao, Lu, Yu, Rybniker, Jan, Dahan, Rony, Huang, Hairong, Barkan, Daniel, Xiang, Ye, Javid, Babak, Freund, Natalia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840946/
https://www.ncbi.nlm.nih.gov/pubmed/33504803
http://dx.doi.org/10.1038/s41467-021-20930-0