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The DNA-helicase HELLS drives ALK(−) ALCL proliferation by the transcriptional control of a cytokinesis-related program

Deregulation of chromatin modifiers, including DNA helicases, is emerging as one of the mechanisms underlying the transformation of anaplastic lymphoma kinase negative (ALK(−)) anaplastic large cell lymphoma (ALCL). We recently identified the DNA-helicase HELLS as central for proficient ALK(−)ALCL p...

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Detalles Bibliográficos
Autores principales: Tameni, Annalisa, Sauta, Elisabetta, Mularoni, Valentina, Torricelli, Federica, Manzotti, Gloria, Inghirami, Giorgio, Bellazzi, Riccardo, Fragliasso, Valentina, Ciarrocchi, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840974/
https://www.ncbi.nlm.nih.gov/pubmed/33504766
http://dx.doi.org/10.1038/s41419-021-03425-0