A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice

Pulsing cellular dynamics in genetic circuits have been shown to provide critical capabilities to cells in stress response, signaling and development. Despite the fascinating discoveries made in the past few years, the mechanisms and functional capabilities of most pulsing systems remain unclear, an...

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Detalles Bibliográficos
Autores principales: Li, Ting, Chen, Xianjun, Qian, Yajie, Shao, Jiawei, Li, Xie, Liu, Shuning, Zhu, Linyong, Zhao, Yuzheng, Ye, Haifeng, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840992/
https://www.ncbi.nlm.nih.gov/pubmed/33504786
http://dx.doi.org/10.1038/s41467-021-20913-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840992/
https://www.ncbi.nlm.nih.gov/pubmed/33504786
http://dx.doi.org/10.1038/s41467-021-20913-1

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