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A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice
Pulsing cellular dynamics in genetic circuits have been shown to provide critical capabilities to cells in stress response, signaling and development. Despite the fascinating discoveries made in the past few years, the mechanisms and functional capabilities of most pulsing systems remain unclear, an...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840992/ https://www.ncbi.nlm.nih.gov/pubmed/33504786 http://dx.doi.org/10.1038/s41467-021-20913-1 |