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Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA
The nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore, effecti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840993/ https://www.ncbi.nlm.nih.gov/pubmed/33504856 http://dx.doi.org/10.1038/s41598-021-81743-1 |