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Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA

The nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore, effecti...

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Detalles Bibliográficos
Autores principales:	Leitner, Peter D., Vietor, Ilja, Huber, Lukas A., Valovka, Taras
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840993/ https://www.ncbi.nlm.nih.gov/pubmed/33504856 http://dx.doi.org/10.1038/s41598-021-81743-1

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