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Reproducibility Problems of Amyloid-β Self-Assembly and How to Deal With Them

The self-assembly of peptides and proteins into amyloid fibrils and other aggregates are linked to several diseases. One of the most studied cases is the peptide amyloid-β (Aβ), found self-assembled in Alzheimer's disease patients' brains. In test tubes, assays with chemically synthesized...

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Detalles Bibliográficos
Autores principales: Faller, Peter, Hureau, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841044/
https://www.ncbi.nlm.nih.gov/pubmed/33520935
http://dx.doi.org/10.3389/fchem.2020.611227