Oxysterol-Binding Protein-Related Protein 8 Inhibits Gastric Cancer Growth Through Induction of ER Stress, Inhibition of Wnt Signaling, and Activation of Apoptosis

Gastric cancer (GC) is the third leading cause of cancer-related mortality worldwide. Oxysterol-binding protein-related protein 8 (ORP8) functions as a sterol sensor that regulates a number of cellular functions. We showed that ORP8 expression was significantly lower in GC tissues and cells. Overexp...

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Detalles Bibliográficos
Autores principales: Guo, Xiaohe, Zhang, Lanfang, Fan, Yingying, Zhang, Dezhong, Qin, Lei, Dong, Shuping, Li, Guangyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841135/
https://www.ncbi.nlm.nih.gov/pubmed/27983927
http://dx.doi.org/10.3727/096504016X14783691306605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841135/
https://www.ncbi.nlm.nih.gov/pubmed/27983927
http://dx.doi.org/10.3727/096504016X14783691306605

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