APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling

The exonuclease activity of Apurinic/apyrimidinic endonuclease 1 (APE1) is responsible for processing matched/mismatched terminus in various DNA repair pathways and for removing nucleoside analogs associated with drug resistance. To fill in the gap of structural basis for exonucleolytic cleavage, we...

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Detalles Bibliográficos
Autores principales: Liu, Tung-Chang, Lin, Chun-Ting, Chang, Kai-Cheng, Guo, Kai-Wei, Wang, Shuying, Chu, Jhih-Wei, Hsiao, Yu-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841161/
https://www.ncbi.nlm.nih.gov/pubmed/33504804
http://dx.doi.org/10.1038/s41467-020-20853-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841161/
https://www.ncbi.nlm.nih.gov/pubmed/33504804
http://dx.doi.org/10.1038/s41467-020-20853-2

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