The RGS-RhoGEFs control the amplitude of YAP1 activation by serum

Actin-dependent mechanisms drive the nuclear translocation of Yap1 to enable its co-activation of transcription factors that induce pro-growth and survival programs. While Rho GTPases are necessary for the nuclear import of YAP1, the relevant Guanine Exchange Factors (GEFs) and GTPase Activating Pro...

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Detalles Bibliográficos
Autores principales: Lane, Brandon S., Heller, Brigitte, Hollenberg, Morley D., Wells, Clark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841162/
https://www.ncbi.nlm.nih.gov/pubmed/33504879
http://dx.doi.org/10.1038/s41598-021-82027-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841162/
https://www.ncbi.nlm.nih.gov/pubmed/33504879
http://dx.doi.org/10.1038/s41598-021-82027-4

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