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NiH-catalyzed asymmetric hydroarylation of N-acyl enamines to chiral benzylamines

Enantiomerically pure chiral amines and related amide derivatives are privilege motifs in many pharmacologically active molecules. In comparison to the well-established hydroamination, the transition metal-catalysed asymmetric hydrofunctionalization of enamines provides a complementary approach for...

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Detalles Bibliográficos
Autores principales: He, Yuli, Song, Huayue, Chen, Jian, Zhu, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841163/
https://www.ncbi.nlm.nih.gov/pubmed/33504793
http://dx.doi.org/10.1038/s41467-020-20888-5