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A Wnt Pathway Activator Induces Apoptosis and Cell Death in Mouse Monocytic Leukemia Cells

A Wnt agonist, 2-amino-4-[3,4-(methylenedioxy)benzylamino]-6-(3-methoxyphenyl) pyrimidine, is a cell-permeable pyrimidine compound that has been shown to mimic the effect of Wnt. In this study, leukemic mouse cell lines, RAW 264.7 and J774.1, were incubated with the Wnt agonist. The Wnt agonist show...

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Detalles Bibliográficos
Autores principales: Kato, Yoshiro, Naiki, Yoshikazu, Komatsu, Takayuki, Takahashi, Kazuko, Nakamura, Jiro, Koide, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841171/
https://www.ncbi.nlm.nih.gov/pubmed/27623760
http://dx.doi.org/10.3727/096504016X14721731148893