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Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model

Esophageal squamous cell cancer is a highly aggressive cancer with a dismal 5-year survival rate. CD47 is a cell transmembrane protein that is involved in cell apoptosis, proliferation, adhesion, migration, and antigen presentation in the immune system. By interacting with signal regulatory protein-...

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Detalles Bibliográficos
Autores principales: Tao, Hua, Qian, Pudong, Wang, Feijiang, Yu, Hongliang, Guo, Yesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841197/
https://www.ncbi.nlm.nih.gov/pubmed/28337964
http://dx.doi.org/10.3727/096504017X14900505020895