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Inhibition of ERK1/2 Signaling Impairs the Promoting Effects of TGF-β1 on Hepatocellular Carcinoma Cell Invasion and Epithelial–Mesenchymal Transition

Transforming growth factor-β (TGF-β) and ERK signaling have been implicated in various human cancers including hepatocellular carcinoma, but the underlying mechanism remains largely unclear. In this study, we aimed to explore the role of ERK1/2 in the regulation of TGF-β’s promoting and suppressive...

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Detalles Bibliográficos
Autores principales: Liu, Ling, Li, Nianfeng, Zhang, Qi, Zhou, Jixiang, Lin, Ling, He, Xinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841251/
https://www.ncbi.nlm.nih.gov/pubmed/28492136
http://dx.doi.org/10.3727/096504017X14938093512742