Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method

To evaluate the biodistribution of hydroxychloroquine (HCQ) in cynomolgus macaques and receive dynamic quantitative relationship between plasma, blood, and lung tissue concentration using the population pharmacokinetic modeling method, seventeen cynomolgus macaques were divided into six groups accor...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Bi, Guofang, Chen, Guiying, Guo, Xuan, Tu, Siqi, Tong, Xiaolin, Xu, Man, Liu, Mengjie, Wang, Bei, Jiang, Hongliang, Wang, Jufeng, Li, Haiyan, Wang, Kun, Liu, Dongyang, Song, Chunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841297/
https://www.ncbi.nlm.nih.gov/pubmed/33519466
http://dx.doi.org/10.3389/fphar.2020.602880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841297/
https://www.ncbi.nlm.nih.gov/pubmed/33519466
http://dx.doi.org/10.3389/fphar.2020.602880

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