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Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method
To evaluate the biodistribution of hydroxychloroquine (HCQ) in cynomolgus macaques and receive dynamic quantitative relationship between plasma, blood, and lung tissue concentration using the population pharmacokinetic modeling method, seventeen cynomolgus macaques were divided into six groups accor...
Autores principales: | Liu, Qi, Bi, Guofang, Chen, Guiying, Guo, Xuan, Tu, Siqi, Tong, Xiaolin, Xu, Man, Liu, Mengjie, Wang, Bei, Jiang, Hongliang, Wang, Jufeng, Li, Haiyan, Wang, Kun, Liu, Dongyang, Song, Chunli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841297/ https://www.ncbi.nlm.nih.gov/pubmed/33519466 http://dx.doi.org/10.3389/fphar.2020.602880 |
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