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Identification of Key Genes in Purine Metabolism as Prognostic Biomarker for Hepatocellular Carcinoma

BACKGROUND: Deregulated purine metabolism is critical for fast-growing tumor cells by providing nucleotide building blocks and cofactors. Importantly, purine antimetabolites belong to the earliest developed anticancer drugs and are still prescribed in clinics today. However, these antimetabolites ca...

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Detalles Bibliográficos
Autores principales: Su, Wen-Jing, Lu, Pei-Zhi, Wu, Yong, Kalpana, Kumari, Yang, Cheng-Kun, Lu, Guo-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841304/
https://www.ncbi.nlm.nih.gov/pubmed/33520699
http://dx.doi.org/10.3389/fonc.2020.583053