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Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study

BACKGROUND: Brain lipid metabolism appears critical for cognitive aging, but whether alterations in the lipidome relate to cognitive decline remains unclear at the system level. METHODS: We studied participants from the Three-City study, a multicentric cohort of older persons, free of dementia at ti...

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Detalles Bibliográficos
Autores principales: Lefèvre-Arbogast, Sophie, Hejblum, Boris P, Helmer, Catherine, Klose, Christian, Manach, Claudine, Low, Dorrain Y, Urpi-Sarda, Mireia, Andres-Lacueva, Cristina, González-Domínguez, Raúl, Aigner, Ludwig, Altendorfer, Barbara, Lucassen, Paul J, Ruigrok, Silvie R, De Lucia, Chiara, Du Preez, Andrea, Proust-Lima, Cécile, Thuret, Sandrine, Korosi, Aniko, Samieri, Cécilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841305/
https://www.ncbi.nlm.nih.gov/pubmed/33508744
http://dx.doi.org/10.1016/j.ebiom.2021.103216