A Clofazimine-Containing Regimen Confers Improved Treatment Outcomes in Macrophages and in a Murine Model of Chronic Progressive Pulmonary Infection Caused by the Mycobacterium avium Complex

Treatment outcomes using the standard regimen (a macrolide, ethambutol, and rifampicin) for Mycobacterium avium complex-pulmonary disease (MAC-PD) remain unsatisfactory. Thus, improved treatment regimens for MAC-PD are required. Clofazimine has recently been revisited as an effective drug against my...

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Detalles Bibliográficos
Autores principales: Lee, Ju Mi, Park, Jiyun, Choi, Sangwon, Jhun, Byung Woo, Kim, Su-Young, Jo, Kyung-Wook, Hong, Jung Joo, Kim, Lee-Han, Shin, Sung Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841306/
https://www.ncbi.nlm.nih.gov/pubmed/33519787
http://dx.doi.org/10.3389/fmicb.2020.626216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841306/
https://www.ncbi.nlm.nih.gov/pubmed/33519787
http://dx.doi.org/10.3389/fmicb.2020.626216

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