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Identification of two highly antigenic epitope markers predicting multiple sclerosis in optic neuritis patients

BACKGROUND: Optic neuritis (ON) can occur as an isolated episode or will develop to multiple sclerosis (MS) a chronic autoimmune disease. What predicts ON progression to MS remains poorly understood. METHODS: We characterised the antibody epitope repertoire in three independent clinical cohorts (dis...

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Detalles Bibliográficos
Autores principales: Sadam, Helle, Pihlak, Arno, Jaago, Mariliis, Pupina, Nadežda, Rähni, Annika, Toots, Maarja, Vaheri, Antti, Nieminen, Janne K., Siuko, Mika, Tienari, Pentti J., Palm, Kaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841498/
https://www.ncbi.nlm.nih.gov/pubmed/33493797
http://dx.doi.org/10.1016/j.ebiom.2021.103211