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Differential Stabilities of Mefloquine-Bound Human and Plasmodium falciparum Acyl-CoA-Binding Proteins

[Image: see text] Toxic effects of pharmacological drugs restrict their robust application against human diseases. Although used as a drug in the combinatorial therapy to treat malaria, the use of mefloquine is not highly recommended because of its adverse effects in humans. Mefloquine inhibits the...

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Detalles Bibliográficos
Autores principales: Kumar, Abhishek, Ghosh, Debasish Kumar, Ranjan, Akash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841788/
https://www.ncbi.nlm.nih.gov/pubmed/33521428
http://dx.doi.org/10.1021/acsomega.0c04582